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diclofenac metabolism liver

IJMS | Free Full-Text | Diclofenac Disrupts the Circadian Clock and through  Complex Cross-Talks Aggravates Immune-Mediated Liver Injury—A  Repeated Dose Study in Minipigs for 28 Days
IJMS | Free Full-Text | Diclofenac Disrupts the Circadian Clock and through Complex Cross-Talks Aggravates Immune-Mediated Liver Injury—A Repeated Dose Study in Minipigs for 28 Days

Protective effects of diclofenac on liver graft preservation
Protective effects of diclofenac on liver graft preservation

Cytochrome P450 3A4-Mediated Interaction of Diclofenac and Quinidine | Drug  Metabolism & Disposition
Cytochrome P450 3A4-Mediated Interaction of Diclofenac and Quinidine | Drug Metabolism & Disposition

Diclofenac - LiverTox - NCBI Bookshelf
Diclofenac - LiverTox - NCBI Bookshelf

Effect of UGT2B7*2 and CYP2C8*4 polymorphisms on diclofenac metabolism -  ScienceDirect
Effect of UGT2B7*2 and CYP2C8*4 polymorphisms on diclofenac metabolism - ScienceDirect

Formation of a Toxic Quinoneimine Metabolite from Diclofenac: A Quantum  Chemical Study | Bentham Science
Formation of a Toxic Quinoneimine Metabolite from Diclofenac: A Quantum Chemical Study | Bentham Science

DETECTION OF A NOVEL REACTIVE METABOLITE OF DICLOFENAC: EVIDENCE FOR  CYP2C9-MEDIATED BIOACTIVATION VIA ARENE OXIDES | Drug Metabolism &  Disposition
DETECTION OF A NOVEL REACTIVE METABOLITE OF DICLOFENAC: EVIDENCE FOR CYP2C9-MEDIATED BIOACTIVATION VIA ARENE OXIDES | Drug Metabolism & Disposition

Roles of diclofenac and its metabolites in immune activation associated  with acute hepatotoxicity in TgCYP3A4/hPXR-humanized mice - ScienceDirect
Roles of diclofenac and its metabolites in immune activation associated with acute hepatotoxicity in TgCYP3A4/hPXR-humanized mice - ScienceDirect

Diclofenac Sodium ER 100mg
Diclofenac Sodium ER 100mg

PDF] Studies on the chemical reactivity of diclofenac acyl glucuronide with  glutathione: identification of diclofenac-S-acyl-glutathione in rat bile. |  Semantic Scholar
PDF] Studies on the chemical reactivity of diclofenac acyl glucuronide with glutathione: identification of diclofenac-S-acyl-glutathione in rat bile. | Semantic Scholar

The pathogenesis of diclofenac induced immunoallergic hepatitis in a canine  model of liver injury | Oncotarget
The pathogenesis of diclofenac induced immunoallergic hepatitis in a canine model of liver injury | Oncotarget

Catalysts | Free Full-Text | Diclofenac Biodegradation by Microorganisms  and with Immobilised Systems—A Review
Catalysts | Free Full-Text | Diclofenac Biodegradation by Microorganisms and with Immobilised Systems—A Review

Diclofenac - an overview | ScienceDirect Topics
Diclofenac - an overview | ScienceDirect Topics

Hepatic Clearance of Reactive Glucuronide Metabolites of Diclofenac in the  Mouse Is Dependent on Multiple ATP-Binding Cassette Efflux Transporters |  Molecular Pharmacology
Hepatic Clearance of Reactive Glucuronide Metabolites of Diclofenac in the Mouse Is Dependent on Multiple ATP-Binding Cassette Efflux Transporters | Molecular Pharmacology

The pharmacokinetics and metabolism of diclofenac in chimeric humanized and  murinized FRG mice | SpringerLink
The pharmacokinetics and metabolism of diclofenac in chimeric humanized and murinized FRG mice | SpringerLink

Hepatic metabolism of diclofenac: role of human CYP in the minor oxidative  pathways - ScienceDirect
Hepatic metabolism of diclofenac: role of human CYP in the minor oxidative pathways - ScienceDirect

Metabolic pathway for the generation of the major [ 14 C]-diclofenac... |  Download Scientific Diagram
Metabolic pathway for the generation of the major [ 14 C]-diclofenac... | Download Scientific Diagram

Bioactivation of Diclofenac in Vitro and in Vivo: Correlation to  Electrochemical Studies | Chemical Research in Toxicology
Bioactivation of Diclofenac in Vitro and in Vivo: Correlation to Electrochemical Studies | Chemical Research in Toxicology

Mitochondrial toxicity of diclofenac and its metabolites via inhibition of  oxidative phosphorylation (ATP synthesis) in rat liver mitochondria:  Possible role in drug induced liver injury (DILI) - ScienceDirect
Mitochondrial toxicity of diclofenac and its metabolites via inhibition of oxidative phosphorylation (ATP synthesis) in rat liver mitochondria: Possible role in drug induced liver injury (DILI) - ScienceDirect

Diclofenac - Wikipedia
Diclofenac - Wikipedia

Diclofenac - an overview | ScienceDirect Topics
Diclofenac - an overview | ScienceDirect Topics

Fig. 4. | Integrated Assessment of Diclofenac Biotransformation,  Pharmacokinetics, and Omics-Based Toxicity in a Three-Dimensional Human  Liver-Immunocompetent Coculture System | Drug Metabolism & Disposition
Fig. 4. | Integrated Assessment of Diclofenac Biotransformation, Pharmacokinetics, and Omics-Based Toxicity in a Three-Dimensional Human Liver-Immunocompetent Coculture System | Drug Metabolism & Disposition

The pharmacokinetics and metabolism of diclofenac in chimeric humanized and  murinized FRG mice | SpringerLink
The pharmacokinetics and metabolism of diclofenac in chimeric humanized and murinized FRG mice | SpringerLink

Figure 1 from MECHANISM-BASED INACTIVATION OF CYP 2 C 11 BY DICLOFENAC |  Semantic Scholar
Figure 1 from MECHANISM-BASED INACTIVATION OF CYP 2 C 11 BY DICLOFENAC | Semantic Scholar

Development of Novel Diclofenac Analogs Designed to Avoid Metabolic  Activation and Hepatocyte Toxicity | ACS Omega
Development of Novel Diclofenac Analogs Designed to Avoid Metabolic Activation and Hepatocyte Toxicity | ACS Omega

PDF) Diclofenac and ketoprofen liver toxicity in rat | Ana Sabo -  Academia.edu
PDF) Diclofenac and ketoprofen liver toxicity in rat | Ana Sabo - Academia.edu

Formation of the Accumulative Human Metabolite and Human-Specific  Glutathione Conjugate of Diclofenac in TK-NOG Chimeric Mice with Humanized  Livers | Drug Metabolism & Disposition
Formation of the Accumulative Human Metabolite and Human-Specific Glutathione Conjugate of Diclofenac in TK-NOG Chimeric Mice with Humanized Livers | Drug Metabolism & Disposition